Research: Large-scale Genomics & Proteomics

R&D of the modern biotechnology heavily relies on large-scale bio data processing. We especially focus on genomics for DNA data and proteomics for protein data. For genomics, we are developing a MapReduce-based method for designing a set of short sequences called primers that can amplify target DNA sequences in PCR experiments. In addition, we are developing a new large-scale method that can detect deseases such as cancer using WGS or WES data generated by NGS technology. For proteomics, we focus on developing a new approach for accurate and fast analysis of tandem mass spectra data with considering protein modifications.

Large-scale Genomics & Proteomics 

Related Projects

A primer-based diagnostic S/W system for detecting disease genes (PI)

DGIST-GIST, Ministry of Science, Korea
March 2015 ~ Dec. 2015

Related Papers

Olfactory Receptor Olfr544 responding to Azelaic Acid Regulates Glucagon Secretion in <alpha>-cells of Mouse Pancreatic Islets

Kang, N., Bahk, Y. Y., Lee, N., Jae, Y., Cho, Y. H., Ku, C. R., Byun, Y., Lee, E. J., Kim, M.-S., and Koo, J.
Biochemical and Biophysical Research Communications (BBRC), 2015 (accepted) (ISSN: 0006-291X, SCI, IF=2.281, co-corresponding author).

Olfactory Marker Protein Expression Is an Indicator of Olfactory Receptor-Associated Events in Non-Olfactory Tissues

Kang, N., Kim, H., Jae, Y., Lee, N., Ku, C. R., Margolis, F., Lee, E. J., Bahk, Y. Y., Kim, M.-S., and Koo, J.
PLOS ONE, 2015 (accepted) (ISSN: 1932-6203, SCI, IF=3.53, co-corresponding author).